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Biochemistry & Physiology: Open Access


Open Access
 
 
 
ISSN: 2168-9652
 
 
 
HOME » JOURNALS » EDITORIALBOARD-BIOCHEMISTRY-PHYSIOLOGY-OPEN-ACCESS
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Editorial Board

 
Stephen P. Mackessy

Editor-in-Chief
Stephen P. Mackessy

University of Northern Colorado
USA
Email: stephen.mackessy@unco.edu
Phone: (970) 351-2429
Fax: (970) 351-2335

University of Northern Colorado
 Biography :

Stephen P. Mackessy is currently Professor of Biology in the School of Biological Sciences at the University of Northern Colorado. His research broadly encompasses the biology of venomous snakes and the biochemistry of snake venoms, and he has published over 100 scientific papers, book chapters and natural history notes, a book (Handbook of Venoms and Toxins of Reptiles - CRC Press) and a special edition of the Journal of Toxicology-Toxin Reviews. His research has included many graduate and undergraduate students, as well as collaborations with colleagues from Singapore, Spain, Mexico, Argentina, Brazil, France and various other universities in the United States. Several ongoing projects are centered on understanding the evolution of venom systems in snakes and the biological significance of venom compositional variation, with a particular interest in the interface of snake ecology/evolution and venom biochemistry/ pharmacology. To this end, broad sampling of venoms from many species of rattlesnakes (Crotalus, Sistrurus) and numerous species of rear-fanged snakes has resulted in extensive fieldwork in the southwestern United States, Mexico, Guam and Southeast Asia. Recent projects have focused on the effects of venoms and toxins on metastatic cell proliferation and the investigation of novel toxins for new drug leads. His research program has been supported by many local, state and national funding agencies. Dr. Mackessy also teaches numerous graduate and undergraduate courses in biomedicine (Toxinology, Current Topics in Biomedical Research, Parasitology), vertebrate biology (Herpetology, Comparative Anatomy, Mammalogy) and introductory courses (Organismal Biology, Scientific Writing, Exploring Biology) at UNC, where he has received awards in recognition of outstanding research and teaching. He serves as the Faculty Fellow for the newly created Office of Undergraduate Research at UNC. He earned a B.A. and an M.A. in Biology (Ecology and Evolution section) at the University of California at Santa Barbara, Department of Biology (with Dr. S. S. Sweet), and his Ph.D. (with a minor in Biochemistry) was received from Washington State University, Department of Zoology (with Dr. K. V. Kardong). He was a postdoctoral Research Associate at Colorado State University, Department of Biochemistry and Molecular Biology (with Dr. A. T. Tu) before joining the School of Biological Sciences at UNC. He has reviewed scientific manuscripts for over 38 journals, was the managing editor of the Journal of Natural Toxins for seven years and is currently on the editorial board of the journals Toxins, Biochemistry & Physiology:Open Access, Journal of Venom Research and The Scientific World Journal. Personal interests include music, traveling, fieldwork with venomous snakes, camping and motorcycles.
 

Biography
 Research Interest :

Venom proteomics, novel compound discovery, snake venom evolution, herpetology, amphibian and reptile conservation.

Research Interest
 Network
 
Lei Yu

Editor-in-Chief
Lei Yu

Rowan University
USA

Rowan University
 Biography :

Lei Yu received his BS and MS degrees from Jilin University. Lei Yu received his PhD in chemistry from Changchun Institute of Applied Chemistry, Chinese Academy of Sciences. Lei Yu has been a postdoctoral associate at Clemson University with Dr. Lei Yu is Echegoyen and at Oakland University with Dr. Xiangqun Zeng. Currently, Lei Yu is an assistant professor in the Department of Chemistry and Biochemistry at Rowan University, New Jersey. Over the years, Lei Yu has devoted most of his research career to the investigation of bioanalytical chemistry, nanoparticles, electrochemistry, chemical and biosensors, macromolecules, drug delivery, and materials chemistry.

Biography
 Research Interest :

Research goals is to understand the biochemical and biophysical procedures at a molecular level.
 

Research Interest
 Network
 
Masayoshi Yamaguchi

Editor-in-Chief
Masayoshi Yamaguchi
Department of Hematology and Medical Oncology
Emory University School of Medicine
Atlanta
USA

Emory University
 Biography :

Masayoshi Yamaguchi, Ph.D., IOM, FAOE, DDG, DG, is Adjunct Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA (2013-); Visiting Professor in Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX, USA (2012–2013); Visiting Professor in Department of Pathobiology, College of Veterinary Medicine, The University of Missouri-Columbia, MO, USA (2012); Visiting Professor in Department of Foods and Nutrition, The University of Georgia, GA, USA (2011 – 2012); Visiting Professor in Division of Endocrinology and Metabolism and Lipids, Department of Medicine, Emory University School of Medicine, GA, USA (2007 – 2011); Professor in Laboratory of Endocrinology and Molecular Metabolism, Graduate School of Nutritional Sciences, University of Shizuoka, Japan (1993 ~ August 2007); Associate Professor in Graduate School of Nutritional Sciences, University of Shizuoka, Japan (1991~1993); Assistant Professor in School of Pharmaceutical Sciences, University of Shizuoka, Japan (1987~1991); Visiting Assistant Professor in The University of Texas Medical School at Huston, USA (1988); Assistant Professor in Shizuoka College of Pharmacy, Japan (1986~1987); Visiting Assistant Professor in Texas Tech University School of Medicine, USA (1985); Visiting Lecturer in The University of Pennsylvania School of Medicine, USA (1981); Research Associate in Shizuoka College of Pharmacy, Japan (1973 ~ 1986). He received a Ph.D. in Pharmaceutical Sciences from Shizuoka College of Pharmacy (1976, Japan). He has completed his B.S. in Pharmaceutical Sciences, Shizuoka, Japan (1971). Dr. Yamaguchi is engaged in the fields of bone and calcium endocrinology and cell calcium signaling since 1971, and these researches are developed in the aspect of biochemistry, molecular biology, endocrinology, metabolism, nutrition, pharmacology, and toxicology. Dr. Yamaguchi has an interesting for cell signaling mechanism, bone biology, nutritional factor and osteoporosis prevention, diabetic osteoporosis, and cancer bone metastasis and osteolysis. Moreover, Dr. Yamaguchi discovered two novel proteins and genes; cell signaling suppressor protein (named regucalcin; 1978) and transcriptional factor RGPR-p117 (regucalcin gene promoter region-related protein; 2001) in mammalian cells. Dr. Yamaguchi generated regucalcin transgenic rats, which were registered as international patents (USA, EU, Japan, and Korea), and this animal is found to induce osteoporosis and hyperlipidemia. Recently, Dr. Yamaguchi proposes that regucalcin is a target molecule in carcinogenesis of various cancer cell types. Currently, the research of regucalcin is focused as a scientific topic. Dr. Yamaguchi published over 500 English articles to professional journals with peer-review. In addition, Dr. Yamaguchi registered over 20 national and international patents in the fields of his research interesting. Dr. Yamaguchi is serving as editors and editorial board members of reputed 40 international Journals. He received many honor and awards; Prize for Sato Memorial Fundation (1992, Japan/USA), Senji Miyata Foundation Award 2005 (Japan), Japan Society for Biomedical Research on Trace Elements Award 2007, The Lifetime Achievement Award from International Biographical Centre (IBC) (2004, England), The World Lifetime Achievement Award from American Biographical Institute (2004, USA), The Distinguished Service to Science Award from IBC (2007, England), and many others. Dr. Yamaguchi is listed in various biographies; Who’s Who in the World (2005-, Marquis Who’s Who, USA), Who’s Who in Sciences and Engineering (2004-, Marquis Who’s Who, USA), International Biographical Dictionary (2006-, IBC, England), and others.

Biography
 Research Interest :

Dr. Yamaguchi is engaged in the fields of bone and calcium endocrinology and cell calcium signaling since 1971, and these researches are developed in the aspect of biochemistry, molecular biology, endocrinology, metabolism, nutrition, pharmacology, and toxicology. Dr. Yamaguchi has an interesting for cell signaling mechanism, bone biology, nutritional factor and osteoporosis prevention, diabetic osteoporosis, and cancer bone metastasis and osteolysis. Moreover, Dr. Yamaguchi discovered two novel proteins and genes; cell signaling suppressor protein (named regucalcin; 1978) and transcriptional factor RGPR-p117 (regucalcin gene promoter region-related protein; 2001) in mammalian cells. Dr. Yamaguchi generated regucalcin transgenic rats, which were registered as international patents (USA, EU, Japan, and Korea), and this animal is found to induce osteoporosis and hyperlipidemia. The research of regucalcin is focused as a scientific topic. Dr. Yamaguchi published over 500 English articles to professional journals with peer-review. In addition, Dr. Yamaguchi registered over 20 national and international patents in the fields of his research interesting.

Research Interest
 Network
 
Kennedy S. Wekesa

Executive Editor
Kennedy S. Wekesa

Alabama State University
USA
 

Alabama State University
 Biography :

Dr. Kennedy S. Wekesa received his BS in Biology from Guilford College, MS in Biology from the University of North Carolina Greensboro and his Ph.D. in Zoology from North Carolina State University under the direction of Dr. John G. Vandenbergh. His graduate work focused on the role of pheromones in regulating reproductive behavior and physiology. After his graduate work he did his postdoctoral research on signaling mechanisms in the vomeronasal organ under the direction of Dr. Robert H.Anholt at North Carolina State University. He is currently employed at Alabama State University where he is the Associate Dean for the College of Science, Mathematics and Technology and Professor of Biology. His lab studies signaling in the vomeronasal system and the roles of pheromones on behavior and physiology.

Biography
 Research Interest :

Signaling in the vomeronasal system, role of pheromones in regulating behavior and physiology.

Research Interest
 Network
 
Smita Mohanty

Executive Editor
Smita Mohanty

Associate Professor
Department of Chemistry
Oklahoma State University
United States
Phone: (405) 744 6636
E-mail: Smita.Mohanty@okstate.edu
Web: chemistry.okstate.edu/mohanty
Read Interview session with Smita Mohanty

Oklahoma State University
 Biography :

Dr. Smita Mohanty received her doctoral degree in Chemistry in 1988 from University of Delhi in India. She conducted postdoctoral studies in University of Washington, Seattle, WA and in New York in Structural Biology.

Biography
 Research Interest :

Research Interests:

Structure-function studeis of both membrane and soluble protiens having critical biological function
High-resolution NMR spectroscopy and protien crystallography for protien structure determination
Computational chemistry for modelling, docking and small molecule library screening
Protien-ligand interaction studies by biochemical and biophysical methods
Molecular Biology including cloning and mutagenesis
 

Research Interest
 Network
 
Mohammad Najafi

Mohammad Najafi
University of Medical Sciences
Tehran

University of Medical Sciences
 Biography :

Dr. Mohammad Najafi received his PhD in Clinical Biochemistry during the period of 2002-2006. He joined the Iums faculty in 2008. Since coming to Iums, he has developed Bioinformatics in the Biochemistry zone in Medical Sciences. He currently teaches postgraduate students the applications of Bioinformatics databases and tools in your researches in Tehran University of Medical Sciences since Iums is merged with Tums. Its researches are focused on phatobiogenesis of atherosclerosis. Moreover, he has focused on the quality control techniques in clinical investigations

Biography
 Research Interest :

Biochemistry, Molecular genetics, Bioinformatics

Research Interest
 Network
 
Sanjoy Chakraborty

Sanjoy Chakraborty
The City University of New York
USA

The City University of New York
 Biography :

Sanjoy Chakraborty
Associate Professor
College of Technology
Department of Biological Sciences
The City University of New York
Brooklyn, New York, 11201-2983, USA
Tel. 718-260-5968

Biography
 Research Interest :
Research Interest
 Network
 
Shile Huang

Shile Huang
Louisiana State University Health Sciences Center
USA

Louisiana State University
 Biography :

Shile Huang began to study the role of mTOR signaling in cancer cell survival/apoptosis during my postdoctoral training, mentored by Dr. Peter J. Houghton at St. Jude Children’s Research Hospital. Since starting the laboratory in Louisiana State University Health Sciences Center in July 2003, He have been studying how mTOR regulates tumor cell motility and how curcumin inhibits mTOR signaling. The laboratory has considerable experience in studying anticancer mechanisms of small molecules, and has generated/collected a variety of reagents (stable cell lines, and adenoviral, retroviral and lentiviral constructs) related to mTOR pathways. He have a record of successful and productive research projects. So he have the expertise necessary to successfully carry out the proposed work.

Biography
 Research Interest :

Motor signaling in tumorigenesis and metastasis; anticancer mechanisms of natural products; neurotoxicity of cadmium.

Research Interest
 Network
 
Giuseppe Di Giovanni

Giuseppe Di Giovanni
University of Malta
Malta

University of Malta
 Biography :

Giuseppe Di Giovanni received his Ph.D. in Neuroscience from the University of Chieti and was a postdoctoral fellow at Yale University, USA. Previously Researcher of Human Physiology at the Faculty of Medicine and Surgery, University of Palermo, he is currently an Associate Professor of Human Physiology at the Medical School of the University of Malta. He is also an Honorary Senior Lecturer of Neuroscience at the University of Cardiff, UK. He has published more than 50 peer-reviewed papers, edited 5 books and 4 special issues of various journals. He is the Maltese representative of the Biomedicine and Molecular Biosciences at COST, the intergovernmental framework for European Cooperation in Science and Technology.

Biography
 Research Interest :

His research focuses on understanding the pathophysiology of monoaminergic systems using electrophysiological and neurochemical approach.

Research Interest
 Network
 
Gao Nan

Gao Nan
The State University of New Jersey
USA

University of New Jersey
 Biography :

Instructor, Department of Genetics, University of Pennsylvania
Postdoc, Department of Genetics, University of Pennsylvania,
Visiting Scholar, University of California, San Francisco
Ph.D., Cell and Developmental Biology, Vanderbilt University
M.S., Shanghai Medical School, Shanghai, China
Bachelor in Medicine, Soochow Medical School, Suzhou, China
 

Biography
 Research Interest :
Research Interest
 Network
 
Robert H. Broyles

Robert H. Broyles
University of Oklahoma Health Sciences Center
USA

The University of Oklahoma
 Biography :

Robert H. Broyles, Founder and President of The Sickle Cell Cure Foundation, earned a BS (chemistry) and PhD (biochemistry) from Wake Forest University and its Medical Center and obtained post-doctoral training with a National Institute of Health fellowship from Florida State University. Dr. Broyles served five years as an Assistant Professor of Zoology at the University of Wisconsin-Milwaukee and 34 years of professorships in the College of Medicine at the University of Oklahoma. His current appointments are Professor of Biochemistry & Molecular Biology and Professor of Pediatrics (Adjunct) at the University of Oklahoma Health Sciences Center (OUHSC). Dr. Broyles has served as Senior Scientist at the National Institutes of Health in the Hematology Program and the Laboratory of Chemical Biology of NIDDK, as a Lecturer in the Embryology Course of the Marine Biological Laboratory in Woods Hole, Massachusetts, and as Research Member of the Free Radical Biology & Aging Research Program at the Oklahoma Medical Research Foundation.
 

Biography
 Research Interest :

Regulation of gene expression as applied to sickle cell disease, malaria, cancer, neurological & cardiovascular diseases, diabetes
Organ culture techniques, especially as applied to liver
Stem cell differentiation and molecular engineering by gene regulation therapy
Natural products & biological molecules as pharmaceuticals/nutraceuticals
 

Research Interest
 Network
 
Cecilia Holloran Marzabadi

Cecilia Holloran Marzabadi
Seton Hall University
USA

Seton Hall University
 Biography :

Dr. Cecilia H. Marzabadi received her Bachelor’s degrees (Chemistry and Biology) and Masters degree (Chemistry) from Saint Louis University She earned her Ph.D. in Chemistry at the University of Missouri- St. Louis. Her doctoral research examined the preparation and reactions of glucal halohydrins. Dr. Marzabadi did post-doctoral research at Hunter College/CUNY under the direction of Professor Richard Franck. Her post-doc project looked at the synthesis of 2-deoxysugars using a cycloaddition/ring opening based approach. In 1999, she was appointed as a Clare Boothe Luce Assistant Professor in chemistry at Seton Hall University. She was promoted to Associate Professor in 2005.  In 2006, she was a Visiting Associate Professor at Harvard Medical School in the lab of Dr. Dennis Kasper studying the innate immunology of a novel class of zwitterionic saccharide. Dr. Marzabadi has been the Associate Chair and Director of Graduate Studies for her department at Seton Hall since 2009.

Biography
 Research Interest :

Dr. Marzabadi’s current research interests lie in several areas of synthetic carbohydrate chemistry. Ongoing projects in her lab include:  the synthesis of septanose C-glycosides and septanose sugars by a ring-opening/ homologation/ ring-closing strategy. Methods are also being developed for the synthesis of simplified analogs of zwitterionic sugars to be studies in immunological assays. Small molecule therapeutics are also being developed from carbohydrate beased-heterocycles. An iodoamidation procedure has been developed for the synthesis of carbohydrate-based oxazolines to be studied as glycosidase inhibitors. A Povarov reaction has been used to construct novel carbohydrate-based quinolines for study as anti-cancer and antibiotic agents. Novel cyclopropanated sugars and glycals have been developed that display efficacy in the treatment of epilepsy and chronic pain management

Research Interest
 Network
 
Jingshi Shen

Jingshi Shen
University of Colorado
USA

University of Colorado
 Biography :

I trained as a molecular and cell biologist in graduate school at Columbia University, where I worked with Dr. Ron Prywes to study the ER stress regulation of ATF6, a membrane-tethered transcription factor activated by ER-Golgi transport and intramembrane proteolysis. During this period, my interest in membrane transport grew stronger. This ultimately prompted me to join Jim Rothman’s laboratory as a Jane Coffin Childs Postdoctoral Fellow to address more fundamental issues in membrane trafficking. A pioneer in membrane biology, Jim discovered a number of central components of membrane transport including SNAREs, NSF and the COPI coat. While in Jim’s group, I addressed long-standing problems in neurobiology and cell biology regarding Sec1/Munc18 (SM) protein function and fusion specificity. In October 2008 I joined the faculty of the University of Colorado-Boulder. 

Biography
 Research Interest :

We investigate the molecular mechanisms of regulated exocytosis using combined tools of biochemical reconstitution, biophysical analysis and cell-based transport assays.

Research Interest
 Network
 
Sung-Kun Kim

Sung-Kun Kim
Baylor University
USA

 

Baylor University
 Biography :

Hanyang University, Department of Chemistry, BS
Hanyang University, Department of Chemistry, MS
Texas Tech University, Department of Chemistry and Biochemistry, PhD
Texas Tech University, Department of Chemistry and Biochemistry, PostDoc
Baylor University, Department of Chemistry and Biochemistry, Assistant Professor
 

Biography
 Research Interest :

Drug Discovery using rational and combinatorial approaches (target enzymes: metallo-beta-lactamases, sulfonucleotidereductases)
Mechanism studies of redox proteins (APS reductases, glutaredoxins, thioredoxins, and arsenatereductase)
 

Research Interest
 Network
 
Moorthy Krishnan

Moorthy Krishnan
Vanderbilt University
USA

Vanderbilt University
 Biography :
Biography
 Research Interest :
Research Interest
 Network
 
Kevin Charles Kemp

Kevin Charles Kemp
University of Bristol
UK

University of Bristol
 Biography :

Dr Kevin Kemp is a researcher within the School of Clinical Neurosciences at the University of Bristol, UK. He read his first degree in Biomedical Sciences at the University of the West of England in 2003, where he went on to receive a PhD in 2007. Prior to his PhD studies Dr Kemp received a distinction for his Masters degree in Transfusion and Transplantation Sciences at the University of Bristol. As a senior post-doctoral scientist at the Multiple Sclerosis and Stem Cell laboratories, University of Bristol, his research interests are now in the therapeutic use of stem cells for neurodegenerative disorders, an area in which he has published many scientific research papers. Dr Kemp has a major role in supervising post-graduate students and clinical research fellows. He has also set up a number of research collaborations through close liaison with researchers from the around the world.

Biography
 Research Interest :

The aims of my current research are to explore new treatments for patients with degenerative ataxias and other neurodegenerative disorders. My research involves investigating the potential of mobilisation (drug induced or transplantation) of human bone marrow-derived stem cells and/or other stem cell populations to promote neuronal cell survival and regeneration.

Research Interest
 Network
 
Yue Ge

Yue Ge
Integrated Systems Toxicology Division
National Health and Environmental Effects Research Laboratory
U.S. Environmental Protection Agency
Research Triangle Park
NC 27711 USA
 

U.S. Environmental Protection Agency
 Biography :

Dr. Ge received his Ph.D. at the University of Michigan, Ann Arbor, USA, where he investigated pathological and physiological mechanisms of Duchenn Muscular Dystrophy by identifying and characterizing disease targets, biomarkers and signaling pathways associated with the disease onset and progression using functional proteomic approaches.  Prior to his Ph.D. studies, he had worked in Walther Oncology Center, Indiana University for four years, where he studied cytokine gene expression in human stem and progenitor cells and gene therapy. Following the completion of his Ph.D. study, Dr. Ge moved to Department of Proteomics at Invitrogen, where he worked as a lead scientist for breast cancer proteomic project focusing on identification of breast cancer biomarkers using Multiplexed Proteomics Technology Platform built within the research team, and a project leader for development of protein assays for the detection and quantification of protein biomarkers.  In 2006, Dr. Ge took the position of Principal Investigator at US Environmental Protection Agency (EPA). His laboratory is working in the emerging field of toxicoproteomics for the development of toxicoproteomics methodologies and applications of the methodologies developed to systematic and high-throughput analysis of toxicity pathways and toxic mechanisms of environmental chemicals, and identification of protein toxicity signatures/biomarkers for human health risk assessment. His research efforts and publications have led to invitations to serve as conference chair and keynote speaker, OMICS session chairs for SETAC, EUROTOX, AES and several other international conferences. He is currently serving as North America Regional Editor for Journal of Integrated OMICS, and Associate Editor for Environmental Health and Toxicology. Dr. Ge is a recipient of multiple US biotechnology patents and EPA Scientific and Technological Achievement Award (STAA). He is currently leading an EPA’s Innovative research project on “Predictive Proteomic Risk Assessment of Chemical Mixtures”

Biography
 Research Interest :

Proteomics and its application to Environmental toxicity research; Chemical mixture toxicity, safety assessment and human health risk assessment; Environmental carcinogenesis research; Biomarker discovery and proteomics technology development; Stem cell biology.

Research Interest
 Network
 
Liangqun Huang

Liangqun Huang
Colorado State University
USA

Colorado State University
 Biography :

Liangqun Huang, PhD is a Research Scientist of Biochemistry and Molecular Biology at the Colorado State University.
Dr. Huang’s work focuses on mechanistic examination of HIV-1 protease autoprocessing, a viral specific reaction responsible for production of the mature protease, and identification and characterization of molecules interfering with protease autoprocessing.  She contributed to establishment of a simple mammalian cell-based functional assay that allows direct quantification of protease autoprocessing. Her work has demonstrated that both the protease sequence and the protease context affect the catalytic site conformation, and flexible catalytic site conformations modulate HIV-1 protease autoprocessing reactions.
Dr. Huang received her B.S. in Microbiology from the Wuhan University, China, in 1987, and her Ph.D. from the Central-South University, China, in 2001 studying effect of hearing loss-linked Connexin31 mutants on gap junction. She received her postdoctoral training in retroviruses at the Colorado State University. Dr. Huang was promoted to a research scientist I in 2011.

Biography
 Research Interest :

My research interests include characterization of the molecular and cellular mechanisms of HIV-1 replication, and development of preventative or therapeutic strategies against HIV-1 infection. I am currently focusing primarily on two major projects: (1) Mechanistic examination of HIV-1 protease autoprocessing, a viral specific reaction responsible for production of the mature protease, and (2) Identification and characterization of molecules interfering with protease autoprocessing.
HIV protease autoprocessing is a highly regulated reaction concomitant with virion release. However, the detailed molecular and cellular mechanisms of autoprocessing regulation remain largely illusive. In an attempt to study protease autoprocessing in vivo, we engineered a cell based fusion precursor model system to examine protease autoprocessing. This system mirrors phenotypes described in other model systems, and allows examination of protease autoprocessing function in the context of live cells by directly monitoring amounts of the fusion precursor and autoprocessing products. By using this system, we have demonstrated both the protease sequence and the protease context affect protease catalytic site conformation, and several non-active site residues as well as residues flanking the protease also regulate embedded protease activity through modulation of the catalytic site conformation.
The advantage of our system is its simplicity without a compromise of sensitivity, allowing for broad application in the examination of the protease autoprocessing mechanism and/or in the identification and characterization of novel anti-HIV drugs. It may also be further developed for structure analysis of protease precursor.

Research Interest
 Network
 
Yunfu Lin

Yunfu Lin
Assistant Professor
Department of Biochemistry and Molecular Biology
Baylor College of Medicine
USA

Baylor College of Medicine
 Biography :

B.A., Beijing Normal University, 1982
M.S., Beijing Normal University, 1985
Ph.D., Fudan University, 1993 

Biography
 Research Interest :

My research interest focuses on understanding the mechanisms of CAG repeat (CTG repeats on the complementary strand) instability using model systems in culture human cells and mice. Expansion of CAG repeat tracts within the human genome causes several neurological diseases such as Huntington's disease, myotonic dystrophy, and several spinocerebellar ataxias. However, the mechanisms leading to repeat instability, as well as disease pathogenesis, are ill-defined. The repeats are unstable in both germline and somatic cells, typically biased to expansion (increasing the number of repeats).

Research Interest
 Network
 
Angel Manteca

Angel Manteca
University of Oviedo
Spain

University of Oviedo
 Biography :

Dr. A. Manteca obtained the Biology degree from the University of Oviedo in 2000 and a PhD-degree in Microbiology, in 2005. After a postdoctoral stay at the University of Southern Denmark, working in quantitative mass spectrometry, he returned to the University of Oviedo as a postdoctoral researcher in 2011. Dr. Manteca has published more than 26 works in the most important microbiological and proteomic journals.

Biography
 Research Interest :

The main research line of Dr. Manteca is focused in the study of Streptomyces biology and differentiation. Streptomyces is a gram positive bacterium characterized by a complex developmental cycle, which is the evolutionary origin of some of the eukaryiotic signalling protein domains (apoptotic ATPases, kinases, caspases, nucleases, etc.). In addition, it is a very important industrial bacterium producing around two thirds of clinically relevant secondary metabolites. A. Manteca was pioneer in the application of new experimental methods to the analysis of Streptomyces biology.

Research Interest
 Network
 
Seema Jawalekar

Seema Jawalekar
Sree Narayana Institute of Medical sciences
India

Sree Narayana Institute of Medical sciences
 Biography :

Seema Jawalekar
Associate Professor
Sree Narayana Institute of Medical sciences
Chalakka, Ernakulam, India
 

Biography
 Research Interest :

My areas of interest are  Kidney diseases, metabolic disorders, Molecular biology, cardiovascular diseases

Research Interest
 Network
 
Sacide Pehlivan

Sacide Pehlivan
Istanbul University, İIstanbul Faculty of Medicine
Department of Medical Biology
Capa - Fatih / ISTANBUL
Office: 0 212 6351168
GSM Tel: 0 532 5231835
E-mail: sacide.pehlivan@istanbul.edu.tr; psacide@hotmail.com

Istanbul University
 Biography :

Assoc.Prof.Dr. Sacide Pehlivan  has received his PhD  in Department of Medical Biology of Hacettepe University during the period of 1992-1997.  Currently, she is working as Assoc.Prof.Dr. in Department of Medical Biology and Genetics of Medical Faculty of Gaziantep University. She has successfully completed his Administrative responsibilities as both teacher and researcher. She is serving as an editorial member of several reputed journals like Acta Oncologica Turcia, Journal of Paediatrics, Turkish Clinics... She has authored  88 research articles. She is a member of Eurepean Human Genetics, Turkish Medical Genetics, Turkish Medical Biology and Genetics.... She has honoured as 13 prizes.

Biography
 Research Interest :

Sacide Pehlivan’s interests  include  Molecular Medicine that represents diagnosis and prenatal diagnosis of human inherited diseasea and molecular mechanisms of different types of cancer and different human disease ( multiple sclerosis, nephrotic syndromes, vitiligo).

Research Interest
 Network
 
William H Konigsberg

William H Konigsberg
Professor
Molecular Biophysics and Biochemistry
Yale University
USA

Yale University
 Biography :

Dr. William H Konigsberg has received his Ph.D. in Organic Chemistry from Columbia University, N.Y. in 1956. Currently, he is working as Professor in Molecular Biophysics and Biochemistry at Yale University. He is serving as an editorial member of reputed journal Proteins: Structure, Function, and Genetics. He is a member of American Society of Microbiologists since 1984.

Biography
 Research Interest :

Blood Coagulation, DNA Replication,Genetics, Proteins and Macromolecules.

Research Interest
 Network
 
Joseph Fomusi Ndisang

Joseph Fomusi Ndisang
Associate Professor
Department of Physiology
College of Medicine
University of Saskatchewan
Canada

 Biography :

Joseph Fomusi Ndisang received postdoctoral training in Physiology at the University of Saskatchewan College of Medicine from 2000-2005. He received a PhD in Pharmacology & Toxicology from the University of Florence, Italy, 2000. He received a Doctor of Pharmacy degree from University of Florence, Italy in 1995. He has received several distinguished awards and distinctions including Fellow of the American Heart Association (FAHA) in 2011.

Biography
 Research Interest :

His research is mainly focused on investigation the role of the heme oxygenase system in hypertension, diabetes (types-1 and -2), and obesity.

Research Interest
 Network
 
Rudi Fasan

Rudi Fasan
Department of Chemistry
University of Rochester
New York
USA

University of Rochester
 Biography :

Dr. Rudi Fasan received his BS in Chemistry from University of Padua (Italy). In 2005, he earned his PhD in Organic Chemistry working with Prof. J.A. Robinson at University of Zurich (Switzerland) on synthesis of beta-hairpin protein epitope mimetics. After a postdoctoral experience with Prof. F.H. Arnold at California Institute of Technology working in the area of P450 engineering and enzyme directed evolution, he joined the University of Rochester as Assistant Professor of Chemistry in 2008. His awards include Swiss National Science Foundation Graduate Fellowship (2001-2005), SNF Postdoctoral Fellowship (2005-2006), Friedrich-Weygand Outstanding Research Award (2007), and Provost Multidisciplinary Award (2011). He is member of the American Chemical Society and Society of Biomolecular Engineering and he serves as reviewer for twelve journals. Dr. Fasan’s research interests lie in the area of bioorganic chemistry, chemical biology, protein engineering, biocatalysis, and chemoenzymatic synthesis. His research currently focuses on the synthesis, molecular evolution, and evaluation of macrocyclic organo-peptide structures for modulation of protein-protein interactions and on the development of P450-centered protein engineering and chemo-enzymatic strategies for selective functionalization of aliphatic C-H bonds in complex molecules.

Biography
 Research Interest :

Dr. Fasan’s research interests lie in the area of bioorganic chemistry, chemical biology, protein engineering, biocatalysis, and chemoenzymatic synthesis. His research currently focuses on the synthesis, molecular evolution, and evaluation of macrocyclic organo-peptide structures for modulation of protein-protein interactions and on the development of P450-centered protein engineering and chemo-enzymatic strategies for selective functionalization of aliphatic C-H bonds in complex molecules.

Research Interest
 Network
 
Justin W. Brown

Justin W. Brown
Department of Biology
James Madison University
USA

James Madison University
 Biography :

Dr. Justin Brown received his PhD in Physiology from East Carolina University where he explored the role of the hypothalamus in the hypothermic response to hemorrhagic shock in rats.  His post-doctoral training at Dartmouth College focused on the role of brainstem serotonin on the thermoregulatory & cardiorespiratory responses to environmental stress during sleep in piglets as a model for Sudden Infant Death Syndrome (SIDS). He is now an associate professor at James Madison University in Harrisonburg VA where he teaches neuroscience & physiology/pathophysiology. He also maintains an active research program with graduate and undergraduate students, and collaborators at the US EPA (Chris Gordon PhD), in exploring the role of brainstem serotonin in the thermoregulatory and cardiovascular responses to exogenous stress in rats as a model for SIDS. His most recent work focuses on the role of ambient and/or preferred temperature in thermoregulatory stress and has implications in the wider field of animal care.

Biography
 Research Interest :

The role of brainstem serotonin in the thermoregulatory and cardiovascular responses to stress as a model for Sudden Infant Death Syndrome. The thermoregulatory responses to thermal stress in rodents – applications in animal care. 

Research Interest
 Network
 
Padmanava Dash

Padmanava Dash
Department of Biology and the Environmental Science Ph.D. program
Jackson State University
USA

Jackson State University
 Biography :

Dr. Dash’s research interest includes water quality, Harmful Algal Blooms (HABs) and phytoplankton ecology, toxic metals, harmful microorganisms, remote sensing, limnology, biological and physical oceanography, and coastal and oceanic biogeochemical processes. HABs are caused by species of tiny plants, phytoplankton. HABs may cause harm through the production of potent chemical toxins or by their accumulated biomass. Due to the human health threats and their negative impact on aquatic life, recreation and tourism, HABs have significant economic and sociocultural impacts worldwide. Additionally, the freshwater systems are affected by eutrophication, leading to undesirable increases in harmful microorganisms (pathogens) and toxic metals. Dr. Dash’s current research interest includes field, laboratory and satellite remote sensing research to study various HAB forming species to enhance the current state of knowledge on detection and mapping of the HABs and thus support state and coastal community efforts to manage human health and fisheries in the region.

Biography
 Research Interest :

Coastal and Estuarine Ecology, Limnology, Environmental Toxicology, Remote Sensing, Harmful Algal Blooms, Biological Oceanography, Water Quality, Biological and Physical Oceanography and Coastal & Oceanic Biogeochemical processes.

Research Interest
 Network
 
Thomas P. West

Thomas P. West, Ph.D
Department of Biology and Microbiology
South Dakota State University
Brookings, SD

South Dakota State University
 Biography :

Dr. Thomas P. West received his PhD in Biochemistry at Texas A&M University in 1980. Dr. West is a Full Professor within the Department of Biology and Microbiology at South Dakota State University on the Brookings campus. He is currently serving as a member of 6 editorial boards. He has authored or coauthored 130 research articles.

Biography
 Research Interest :

His research interests are in the field of microbial biochemistry. His current research is investigating biomass-based specialty chemical production by microorganisms, microbial production of commercially important polysaccharide gums and the regulation of pyrimidine metabolism at the level of enzyme synthesis and enzyme activity in pseudomonads and related species.

Research Interest
 Network
 
Vani Nilakantan

Vani Nilakantan, PhD
Director
Investigator-Initiated Sponsored Research
Aurora Research Institute
Milwaukee, WI 53234
USA

Aurora Research Institute
 Biography :

Dr. Vani Nilakantan is the Director of Investigator-Initiated Sponsored Research at Aurora Health Care. She provides leadership over clinical research activities and ensure that research priorities are in alignment with Aurora Health Care’s mission and strategic priorities. Dr. Nilakantan has created effective collaborative partnerships with senior administrative leadership, clinical system leaders and medical staff and is responsible for developing research programs in partnership with academia and industry. In her role as Director of the Sponsored Programs Office, she has oversight over federal, state, industry and foundation grants. Dr. Nilakantan is an ad-hoc reviewer for Kidney International, British Journal of Urology, Neuroscience India, PPAR Research, Free Radicals in Biology and Medicine and is on the editorial board for Journal of Clinical Rehabilitative Tissue Engineering Research and BioMed Research International. Dr. Nilakantan has held leadership roles in institutional, local and national committees including the Wisconsin Network for Health Research, Aurora Medical Directors Research Council, Aurora Cardiovascular Research Committee, Cancer Clinical Leadership Research Subcommittee, Aurora- AUWMG Research Committee, Animal Care and Use Committee, Aurora- Conflict of Interest Taskforce, MCW -Admissions Committee, MCW- Co-Chair Program Committee Women’s Faculty Council, International Society of Heart and Lung Transplantation - Quality of Life Scientific Council.

Biography
 Research Interest :

Prior to joining Aurora Health Care, Dr. Nilakantan was an Assistant Professor of Surgery at the Medical College of Wisconsin (MCW) where she led a research program in ischemic acute kidney injury and renal protection in kidney transplantation. Her work has been funded by intramural and extramural funding from AHA and NIH. Her collaborations with other investigators have led to 3 grants, 29 peer-reviewed publications and numerous presentations at national conferences Her current research interests are in studying racial disparities in organ transplantation and in the identification of novel serum diagnostic and prognostic biomarkers in cardiac injury and acute kidney injury. She is collaborating with investigators at UWM College of Health Sciences (Informatics) to develop tools and algorithms for building a clinical decision support module at Aurora Health Care for risk stratification of acute kidney injury. To this end, she and the investigators are UWM are submitting grants to national agencies in a joint manner.

Research Interest
 Network
 
Ajay Singh

Ajay Singh, Ph.D
Assistant Professor  of Oncologic Sciences
University of South Alabama Mitchell Cancer Institute (USAMCI)
USA

University of South Alabama Mitchell Cancer Institute
 Biography :

Ajay Singh, Ph.D., is an Assistant Professor of Oncologic Sciences at University of South Alabama Mitchell Cancer Institute (USAMCI). Dr. Singh received a Master’s degree in Biotechnology from Aligarh Muslim University and graduated from the Devi Ahilya University, Indore, India. He completed a short post-doctoral fellowship in the Department of Biochemistry and Molecular Biology at University of Nebraska Medical Center, Omaha, Nebraska. He later attained a research faculty position in the same department, and joined USAMCI in 2009 as a tenure-track faculty. Studies in Dr. Singh’s laboratory have been supported through state and federal grants. He was awarded funds from State of Nebraska for two consecutive years (2007 and 2008) and one grant each from National Cancer Institute (NCI) and Department of Defense (DOD) to support his research. Dr. Singh serves on regional, national and international panels to review research proposals for funding considerations.

Biography
 Research Interest :

Major focus of Dr. Singh’s research is to delineate the molecular mechanisms underlying the aggressive and therapy-resistant behavior of cancer cells. In particular, his lab is investigating the role of microRNAs and tumor microenvironment in facilitating growth, epithelial to mesenchymal transition (EMT), metastasis and drug-resistance of pancreatic and prostate tumor cells. Earlier studies of Dr. Singh identified a mucin gene, MUC4, to be of pathological significance in pancreatic cancer progression and metastasis. MUC4 is an aberrantly expressed glycoprotein in pancreatic cancer exhibiting no expression in the normal pancreas. Recently, his team identified a novel microRNA-mediated mechanism involved in its deregulation in pancreatic cancer. Dr. Singh’s research has also revealed that CXCL12-CXCR4 signaling axis, an exemplary of tumor-microenvironment interaction, promotes drug-resistance in pancreatic cancer cells. In additional studies, his group has identified protein phosphatase 2A (PP2A) as a novel therapeutic target in prostate cancer. They have shown that PP2A activity is inversely associated with androgen-independent growth of prostate cancer cells through a novel mechanism, whereby loss of PP2A-mediated checkpoints leads to the activation of Akt and ERK and partially sustains androgen receptor signaling under steroid-deprived condition. The findings from Dr. Singh’s lab offer potential therapeutic implications for microRNAs, PP2A and tumor-microenvironment in highly aggressive and therapy-resistant pancreatic and/or prostate malignancies.

Research Interest
 Network
 
Bhagelu Ram Achyut

Bhagelu Ram Achyut
Post Doctoral Fellow
Department of Biochemistry and Molecular Biology
Cancer Center
Georgia Regents University
USA
Read Interview session with Bhagelu Ram Achyut

Georgia Regents University
 Biography :

I am a postdoctoral fellow in Cellular and Molecular Imaging Laboratory, Radiology, Henry Ford Health System, MI. Current goal is to discover and alter the signature miRNAs in tumor cell secreted exosomes to reprogram the microenvironment and control neovascularization in glioblastoma. I completed Ph.D. (2009) in the Department of Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, India. I investigated association of genetic polymorphisms of cytokines and other inflammatory molecules with human gastritis and precancerous gastric lesions. Later, I joined Indian Institute of Toxicology Research, India as a scientist in 2008.I joined laboratory of Cancer Biology and Genetics, NCI-NIH for advanced postdoctoral training in 2009. I investigated inflammation mediated alterations could drive cancer development upon stromal abrogation of TGFβ signaling. My research was published in PLoS Genetics and highlighted in Nature Reviews of Cancer Journal. This experience allowed me to gain laboratory skills and a solid foundation in basic science research.

Biography
 Research Interest :

Cancer Biology (Anti-angiogenesis in Glioblastoma), Cancer Biology and Genetics (Anti-inflammation in Squamous cell carcinoma of the Forestomach), Neurotoxicology (Manganese nanoparticle induced neurotoxicity in rat), Medical Genetics (Role of cytokine gene polymorphisms in human gastritis susceptibility), Biotechnology

Research Interest
 Network
 
Kenneth Maiese

Kenneth Maiese
Head of Translational Medicine and External Innovation
Professor, Chair, & Chief of Service, Neurology and Neurosciences
Rutgers-New Jersey Med School
New Jersey, USA

Rutgers-New Jersey Med School
 Biography :

Kenneth Maiese is Head of Translational Medicine and External Innovation, and past Professor, Chair, and Chief of Service of the Department of Neurology and Neurosciences at Rutgers. He graduated from the University of Pennsylvania Suma cum Laude with Distinction, was a Teagle and Grupe Scholar at Weill Cornell Medical College, and trained as a physician-scientist at the NIH. Dr. Maiese has received outstanding teaching awards and election to Americas Top Physicians, the Best of U.S. Physicians, and Top Doctors. He is a top cited author with continuous funding from multiple agencies such as the American Diabetes Association, the American Heart Association, the Bugher Foundation, and the NIH. Dr. Maiese holds several patents, has over 350 publications and has authored 5 books. Dr. Maiese also serves as the Editor-in-Chief, Associate Editor, or editorial board member for more than 80 journals as well as on multiple executive, technology, and scientific advisory councils.

Biography
 Research Interest :

translational drug development, oxidative stress, cell signaling, transcription factors, apoptosis, autophagy, biomarkers, growth factors, metabotropic receptors, cancer, stem cells

Research Interest
 Network
 
Qun Wang

Qun Wang
Assistant Professor
Department of Chemical  and  Biological  Engineering, 
Department  of  Civil,
Construction and Environmental Engineering,
Iowa State University
USA

Iowa State University
 Biography :

Dr. Qun Wang works as assistant professor with a joint appointment in the Department of Chemical and Biological Engineering and the Department of Civil, Construction and Environmental Engineering at Iowa State University, as well as associate scientist at the Ames National Laboratory of Department of Energy. He got his Ph.D. in Chemical and Petroleum Engineering from University of Kansas in 2010. He also got another Ph.D. in Environmental Science and Engineering from Wuhan University in 2007. Before he joined Iowa State University, he has worked as Jorge Heller Postdoctoral Fellow in Professor Robert Langer’s Lab at MIT and Harvard Medical School. He serves as Associate Editor of Journal of Biomedical Nanotechnology and Editorial Board Member of International Journal of Pharmaceutics.

Biography
 Research Interest :

Dr. Wang’s areas of interest include Biomaterials, Intestinal Engineering, Nanotechnology, and Drug Delivery. In Iowa State University, Dr. Wang BINDs his research in these areas to provide innovative solutions and products for human health. His current research focuses on developing functional materials for biomedicine. Functionalized design represents a powerful strategy for developing next generation materials for numerous emerging applications, including energy, pharmaceutics, environment and medicine. Dr. Wang will employ his multidisciplinary expertise in materials science, stem cells, microfabrication, and pharmaceutical chemistry to address and resolve the challenging problems of public health.

Research Interest
 Network
 
Deepak Kumar

Deepak Kumar
Associate Professor of Biology
Chair, Department of Biology, Chemistry and Physics
Co-Director, UDC Cancer Research and Education Academy
Cancer Research Laboratory       
University of the District of Columbia
Washington DC 20008

University of the District of Columbia
 Biography :
Biography
 Research Interest :

Molecular basis of Cancer Prevention, MicroRNAs in Prostate Cancer, Molecular Mechanisms of Apoptosis, Biomarkers for early cancer detection and target for drug development, Cancer Health Disparity

Research Interest
 Network
 
Shah Alam Khan

Shah Alam Khan
Associate Professor
Oman Medical College
Muscat, Oman
Read Interview session with Shah Alam Khan

Oman Medical College
 Biography :

Dr. Shah Alam Khan is currently working as an Associate Professor of Pharmaceutical Medicinal Chemistry in the department of Pharmacy at Oman Medical College, Muscat, Oman (affiliated to West Virginia University, USA He received his Ph.D. from Jamia Hamdard University, New Delhi, in 2003 for studying role and chemistry of Silybum marianum, silymarin and its synthetic analogues in the hepatoprotection. He is also recipient of Government of India, Junior research fellowship (JRF, GATE) and Senior Research fellowship (SRF, CSIR) for pursuing masters and doctorate. He has published/presented more than 50 research articles in the national and international journal of repute. He is editorial board member of many international journals and has reviewed scientific papers in field of Pharmacy and science for more than 20 journals. He has supervised 15 undergraduate and post graduate research projects, two of them were awarded first and second prize in poster presentation category at international conferences. He has been invited as guest speaker in many conferences. He was awarded ‘Best Teacher’ in Pharmacy at Oman Medical College for the academic year 2010-11 and 2011-12 consecutively. He is life member of many professional bodies such as IPA, IPGA and APTI.

Biography
 Research Interest :

Synthesis and biological activity of Medicinal compounds of pharmaceutical interest

Chemistry and Pharmacological evaluations of natural products for antihepatotoxic, antidiabetic, antiinflamatory and anticancer activities.

Pharmaceutical analysis of drugs.

Research Interest
 Network
 
Kavish Ramessur

Kavish Ramessur
Researcher
SSR Medical College 
Belle Rive, Mauritius

SSR Medical College
 Biography :

I am certified in Biostatistics and Epidemiology from Harvard Medical School with over a dozen research publications in reputed Medical Journals. I have also authored four medical books – two of which are research theses and two are Textbooks of Biochemistry for Medical Students. The latter have received international acclaim and are being used as standard texts in Medical Schools worldwide. I also am the webmaster of “Biochemistry for Medics,” a non-profit website aimed at making Biochemistry more accessible to medical students; a site that receives over five thousand visitors every day. My field of expertise is “Oxidative Stress” which I feel, is at the root of several pathologies and whose curtailment shall open new vistas towards newer therapeutic approaches.

Biography
 Research Interest :
Research Interest
 Network
 
Basilio Vagner

Basilio Vagner
Private practice
Medellin Poblado Clinic
Colombia

Medellin Poblado Clinic
 Biography :

I am a clinical neurologist,in the city of Medellin Colombia; I work in research and care of patients with multiple sclerosis. I have a master in multiple sclerosis. I am coordinator of multiple sclerosis and demyelinating disease in the institution medicate. I am a teacher ingeneral neurology in medical schools and university Pontificia Bolivariana University of Antioquia,in the area ofundergraduateand graduate studentstointernal medicine,psychiatry,and neurology currentlyI haveseveral publicationsinbasic and clinical sciences

Biography
 Research Interest :
Research Interest
 Network
 
Soraya L. Valles

Soraya L. Vallés
Assistant professor
Department of Physiology,
School of Medicine
University of Valencia
Spain

University of Valencia
 Biography :

In 1990 I graduated in Biological Science at the University of Valencia and remained there to undertake a PhD under the supervision of Consuelo Guerri at Research Institution (Instituto de Investigaciones Citológicas), which I completed in 1996. During my PhD my dissertation was “Changes of astroglia intermediate filaments gene expression during rat brain development: Effect of alcohol exposure”. I analyze the events which occur during the early stages of astrogliogenesis during brain development, using “in vivo” and “in vitro” experiments. I did experiments in cells in culture primary as radial glia (stem cells in brain), astrocytes and neurons. In 1997 I joined Eva Qwanstrom’s group at the Hallamshire Hospital (University of Sheffiel) in Sheffield, UK and spent three years involved in the identification of an adhesion-regulated subunit of the interleukin-1 (IL-1) receptor complex. I was working in immunology, cytokines, inflammation processes and matrix regulation of IL-1 responses. In 2000 I returned to Spain at Department of Physiology, Medicine Faculty of Valencia. University of Valencia and I were appointed to a part-time position as Lectureship. In 2004 I was appointed to a fixed-term position as permanent University Lecturer at this department in the University of Valencia. During this time I was involved in the mechanisms of oxidative stress in the generation of Alzheimer’s disease with Jose Viña’s group. Also at this time I developed my lectures with Luis Such’s group with who I learned a lot about physiology and how to do a correct lecturer to pupils in my our department.

Biography
 Research Interest :

At this moment I work in Alzheimer’s diseases and in inflammation and oxidative stress mechanisms. Also I am working in Central Nervous System and it control cancer by hormones. At this moment, I would like to work in precursor cells and the subsequently ability to further differentiate into neurons and astroytes inside the brain. I order a grant from my sanity government and I still waiting for the resolution grant, about stem cells and brain.

Research Interest
 Network
 
Zhou J. Deng

Zhou J. Deng
Postdoctoral Researcher at MIT
Massachusetts Institute of Technology
Cambridge

Massachusetts Institute of Technology
 Biography :

Dr. Jason Deng is an Early Career Research Fellow awarded by the National Health and Medical Research Council, Australia in 2013. Since 2011, Jason has joined Massachusetts Institute of Technology as a postdoctoral researcher, working with Professor Paula Hammond at Koch Institute for Integrative Cancer Research. Jason received his PhD in biomedical sciences at the University of Queensland, Australia in 2011with distinction of Dean’s award in research excellence.

Biography
 Research Interest :

Jason’s research has been focusing on the interdisciplinary field of Nano-Biosciences: investigating the interactions of nanomaterials with biological systems, developing new type of cancer therapeutics using nanotechnology, and promoting translation of benchtop research to bedside medicine. His work involves nanomedicine, drug and siRNA delivery, combination therapeutics development, nanotoxicology, cell-based assay development for drug discovery, biomarker discovery and cancer diagnostics. Jason published as the first author in prestigious journals such as Nature Nanotechnology, ACS Nano, and Nanotoxicology; while his collaborative work has been published in Lancet, Advanced Materials, Advanced Healthcare Materials and Scientific Reports.

Research Interest
 Network
 
Kamil Kuca

Kamil Kuca
Research and Development,
Department of Chemistry,
Faculty of Science,
University of Hradec Kralove,
Hradec Kralove,
Czech Republic

University of Hradec Kralove
 Biography :

• Research and Development, Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic (since 2013)

• Head, Center for Transfer of Biomedical Technologies, University Hospital, Hradec Kralove, Czech Republic (since 2012) • Head, Biomedical Research Center, University Hospital, Hradec Kralove, Czech Republic (since 2011)

• Vice-Dean for Research - Faculty of Military Health Sciences, University of Defense, Hradec Kralove Czech Republic (2009-2012)

• Research and Development at the Centre of Advanced Studies, Faculty of Military Health Sciences, University of Defense, Hradec Kralove, Czech Republic (2006-2009)

• Lecturer at the Department of Chemistry, Faculty of Sciences, J.E. Purkinje University, Usti nad Labem, Czech Republic (2006-2012)

• University teacher and Research fellow at the Department of Toxicology, Faculty of Military Health Sciences, University of Defense, Hradec Kralove CZ (2001-2006)

Biography
 Research Interest :

Military toxicology; Acetylcholinesterase reactivators as treatment of nerve agent and pesticide intoxications; Acetylcholinesterase inhibitors in Alzheimer´s disease and Myasthenia Gravis treatment; Synthesis of the detergents as disinfectants, decontamination means and environment for micellar catalysis; Drug design and Development; Chemical warfare agents; Biological warfare agents; Pharmaceutical Industry; Project Management; Scientific Management; Technology Transfer; Commercialization; Toxins.

Research Interest
 Network
 
Mingjie Chen

Mingjie Chen
Senior Research Scientist
University of Missouri
Columbia
United States

University of Missouri
 Biography :

I was born in a rural village of central China, and I spent my childhood there until I was 15. My parents are farmers, but only had a small piece of land for food production due to the land reform and population explosion. My parents areilliteracy, but they gave his kids chance to go to public schools for education.After school I helped my parents for various chores. My parents survived the “Great hunger” which happened at late 1950s in China;I can’t image how they managed to raise up our four siblings. Their stories of struggle to survival deeply influenced me. Although I left that land that brought me up, I can’t stop thinking what I could do to help those that still live like my parents, which inspired me to a journey of plant science research.

Biography
 Research Interest :

My long-term research interest is to understand the biochemical and molecularbasis underpinning various traits that plants gained during their evolutionary history, and apply this knowledge to crop species for improved growth performance, higher yield, and better quality. Currently, my research covers two major topics: 1) The metabolic mechanisms that affect seed composition, storage reserve accumulation or remobilization; 2) The biochemical and molecularbasis of plant tolerance to abiotic stress (cold, freezing, heat and draught stress etc.), especially the membrane lipid desaturation for plant stress response. To address the complexity of these biological questions of interest, various traditional and emerging new techniques will be applied, these include but not limit to genetics, biochemistry, molecular biology, physiology, –omics-based system biology and statistical modeling.

Research Interest
 Network
 
Hiroyuki Hirai

Hiroyuki Hirai
Department of Genetics,
Cell Biology and Development
Stem Cell Institute
University of Minnesota
Minneapolis, USA

University of Minnesota
 Biography :

Dr. Hirai, Research Associate of Genetics, Cell Biology and Development at the University of Minnesota, is an investigator of the Stem Cell Institute and the Minnesota Supercomputing Institute. He received his Ph.D. in Biochemistry from Tokyo Medical and Dental University. He studied muscle stem cell biology and therapy at Stem Cell Institute, University of Minnesota as a postdoctoral fellow. He then studied biochemical analysis of nuclear remodeling in somatic cell nuclear cloning. Recently he fused the transactivation domain (TAD) of MyoD to the pluripotency gene Oct3/4 and radically improved the efficiency of making iPSCs. In addition, fusion of the MyoD TAD to the cardiac transcription factor Mef2c facilitates the direct reprogramming of non-cardiac fibroblasts to cardiomyocyte-like cells.

Biography
 Research Interest :

Dr. Hirai's current research interests are to develop a transdifferentiation strategy and stem cell biology. These studies are expected to contribute to the development of celluar/gene therapy and regenerative medicine. He has been investigating progenitor cells, somatic stem cells and induced pluripotent stem cells (iPSCs) of mouse and human. He continues the research of other regulators necessary for the direct reprogramming and iPSCs reprogramming.

Research Interest
 Network
 
Divya Patel

Divya Patel, Ph.D
Center for Cancer Research and Therapeutic Development
Clark Atlanta University,
Atlanta, Georgia

Clark Atlanta University
 Biography :

Dr. Divya Patel received her Master’s in Microbiology and Ph.D. in Biochemistry from The Maharaja Sayajirao University of Baroda, Baroda, India. She then moved to USA to pursue postdoctoral research at Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL where her work focused on generating RNA Aptamers against immunotherapeutically important target molecules belonging to the tumor necrosis factor (TNF) receptor super family. Dr. Patel is currently continuing her postdoctoral training at Clark Atlanta University’s Center for Cancer Research and Therapeutic Development (CCRTD) and her research concentrates on exploring the role of members of bHLH family of transcription factors in prostate cancer development and progression.

Biography
 Research Interest :

My research focusses on human medicine with the goal of identifying key disease (specifically cancer) mechanisms and targets. With this aim, my current research work concentrates on exploring the role of members of bHLH family of transcription factors, specifically E2A (TCF3) in prostate cancer development and progression. E2A is known to regulate transcription of target genes by homo- or heterodimerization with other bHLH proteins such as MyoD, Mash, NeuroD and Id family of helix loop helix proteins. In general, E2A promotes cell differentiation, acts as a negative regulator of cell proliferation in normal cells and cancer cell lines and is required for normal B-cell development. Given the diverse biological pathways regulated/ influenced by E2A little is known about its expression in prostate cancer. My project therefore involves trying to investigate the mechanism of regulation of E2A in prostate cancer which could either be epigenetic or by gene fusion and chromosomal translocations or androgen receptor dependent. I was also involved in generating RNA Aptamers against immunotherapeutically important target molecules belonging to the tumor necrosis factor (TNF) receptor super family such as OX40 (CD134, TNFRSF4) and 4-1BB (CD137, TNFRSF9). Aptamers are single stranded oligonucleotides capable of binding to their target molecules with high affinity and specificity. They are derived by a process called SELEX (Systematic Evolution of Ligands by EXponential enrichment). Unlike monoclonal antibodies, aptamers have low molecular weights, are chemically synthesized and non immunogenic. Thus, aptamers can serve as promising probes for molecular recognition for diagnostic and therapeutic purposes.

Research Interest
 Network
 
Banudevi Sivanantham
Drug Delivery lab, Centre for Nanotechnology and Advanced Biomaterials (CeNTAB),
India



SASTRA University
 Biography :

Dr.Banudevi Sivanantham received her B.Sc (2000) in Biochemistry and M.Sc in Biochemistry (2002) from University of Madras, as well as M.Phil (2004) in Endocrinology and Ph.D (2011) in Biochemistry-Endocrinology from Dr.ALM Post graduate institute of basic medical sciences, University of Madras. She also served as lecturer (2011-2012) in Valliammal College for Women, University of Madras, India for teaching biochemistry subjects for under and post graduates. She is currently postdoctoral fellow scientist in SASTRA University, Tanjore, India. Her areas of research interest include oral and prostate oncology, cell signaling pathway, stem cell technology, cross talk signaling, combinational treatment strategy and Drug delivery system. She is also has hobbies such as hand crafting, throw ball, shuttle cock and music. She was born in 1980 in Chennai, India

Biography
 Research Interest :

1) Investigation of multiple cell signaling pathway involved in oral and prostate cancer
2) Eludicate the cross-talk signaling pathways and cancer biology
3) Combinational strategy for treatment of oral cancer and prostate cancer
4) Drug delivery system and oral cancer

Research Interest
 Network
 
Gregory Lee

Gregory Lee
UBC Center for Reproductive Health
University of British Columbia
Vancouver, Canada

University of British Columbia
 Biography :

Upon completion of his Ph D degree in Biophysical Chemistry at California Institute of Technology in 1972, he joined UCSD as a NIH Postdoctoral Fellow to carry out pioneer work on general ligand affinity chromatography. In 1976, he studied enzymology and biochemical genetic at the National Institute of Health and in 1981, he was appointed as a faculty member and director of the Andrology Laboratory at the University of British Columbia. During the last two decades, he has created numerous monoclonal antibodies for diagnostic and therapeutic applications in human health care, including RP215 and GHR106 for potential use as anti-cancer drugs.

Biography
 Research Interest :

Research and Development of Antibody-Based Anti-Cancer Drugs

- RP215 monoclonal antibody was shown to recognize specifically a carbohydrate-associated epitope located on the variable regions of cancer cell expressed immunoglobulins, designated in general as CA215.

- Structural elucidation of carbohydrate-associated epitope in CA215 which is recognized by RP215 monoclonal antibody (Mab)

- Humanizations of RP215 Mab for preclinical studies

- Generations of Rat anti-idiotype Mabs as candidates for the development of anti-cancer vaccines in humans

- Establishment of an Anti-GnRH receptor Mab, GHR106, as a substitute of short-acting GnRH analogs for antibody-based anti-cancer drugs, as well as preclinical studies.

- Elucidation of mechanisms of action for RP215 and GHR106 as antibody-based anti-cancer drugs.

- Elucidation of a carbohydrate-associated epitope recognized by RP215 monoclonal antibody.

Research Interest
 Network
 
Mahmoud Balbaa

Mahmoud Balbaa
Department of Biochemistry
Faculty of Science
Alexandria University
Egypt
Read Interview session with Mahmoud Balbaa

Alexandria University
 Biography :

Professor of Biochemistry, Beirut Arab University, Lebanon. Professor (2009–up to date).

Head of Department of Biochemistry, Faculty of Science, Alexandria University, Egypt (2007–2009).

Professor of Biochemistry, Faculty of Science, Alexandria University, Egypt (1999–2002; 2006-2009) and University of Qatar, Doha, State of Qatar (2002–2006).

Assistant Professor of biochemistry, Faculty of Science, Alexandria University, Egypt (1994–1999).

Lecturer of biochemistry, Faculty of Science, Alexandria University, Egypt (1988–1994). 

Biography
 Research Interest :

The study of enzyme inhibition by newly synthesized structures for the establishment of biologically active compounds important for drug design or medicinal chemistry.

The study of enzymatic variation and some signaling pathways in some diseases such as Diabetes mellitus.

The characterization of the enzyme in patients and healthy individuals is studied in a whole investigation of biomarkers of a parasitic or hereditary disease.

The detection of the biochemical changes occurring is parasitic diseases such as schistosomiasis and faschioliasis by studying the characterization of many different enzymes in these diseases. This includes the study of enzymes involved in biological oxidation and cell signaling.

Research Interest
 Network
 
Abdel-Aziz Fatouh Abdel-Aziz

Abdel-Aziz Fatouh Abdel-Aziz
Faculty of Science,
Mansoura University, Mansoura,
P.O.Box 35516, Egypt

Mansoura University
 Biography :

- 2009 –until now, Professor/consultant of Biochemistry, Faculty of Science, Mansoura University, Mansoura, Egypt.

- 2009 – until now, Director of University Development Center, Mansoura University, Egypt.

- Responsible for teaching academic courses for undergraduate and postgraduate students, examination, training the graduating students during summer training period, research projects,research supervision, consulting the students cultural activities and quality assurance program in Chemistry and Biochemistry.

- Co-coordinator of Biochemistry program, Faculty of Science, Mansoura University.

- Supervisors of many Masters and P.hD. theses in Biochemistry.

- Author of more than 40 papers

- Membership of Egyptian biochemistry and molecular Biology Society.

- Membership of Egyptian Chemical Society.

- Membership of American Chemical Society

Biography
 Research Interest :

Water and Mineral metabolism, Applied, cellular and clinical biochemistry, Practical courses in biochemistry, Drug metabolism and drug-drug interaction, Advanced metabolism, Free radical and antioxidants in health and diseases, Hormones and signal transduction and related disorders, Lipids and lipoproteins disorders, Inborn error of metabolism

Research Interest
 Network
 
Syed Saleem Husain

Syed Saleem Husain
Department of Medical Chemistry
Faculty of Applied Medical Sciences
Jazan University
Kingdom of Saudi Arabia

Jazan University
 Biography :

Dr Syed Saleem Husain aka Saleem Saim, age 48, is an Assistant Professor in Medical Chemistry Division, Faculty of Applied Medical Sciences, Jazan University, Jazan, Saudi Arabia. He completed his PhD from Industrial Toxicology Research Center, Lucknow, India, as a Research Fellow, in a project on Neurobehavioral Toxicity of Cadmium in relation to protein malnutrition, sponsored by Indian Council of Medical Research, New Delhi, India. He also holds a master degree in English language and has edited and authored many books. He is a widely acclaimed English poet and writer, published by his pen-name “Saleem Saim”. He has recently published a book entitled, ‘Chemical Studies on Toxic Effects of Cadmium’, published by Lambert Academic Publishing, Germany and a research paper “Studies on Hepato and Renal Toxicity of Cadmium on Normal and Protein Malnourished Rats”, Syed Saleem Husain, J. of Material Sciences & Engineering, 2013, 2-3”, (http://dx.doi.org/10.4172/2169-0022.1000129). He is a reviewer of refereed journals and researcher in the field of heavy metal toxicology.

Biography
 Research Interest :

Techniques on Neurotoxicology, Neurosciences, Applied Science, Toxic Effects of Heavy Metals on Human Brain, Material Sciences and Engineering, Neurobehavioral Impact of Protein Malnutrition, Industrial Toxicology

Research Interest
 Network
 
Amol Suryawanshi

Amol Suryawanshi
Department of Ophthalmology
Tufts University School of Medicine
Boston, MA

Tufts University
 Biography :

Dr. Suryawanshi received his DVM degree from Bomaby Veterinary College, India and MS in Biochemistry from Indian Veterinary Research Institute, India. He then completed his PhD in Comparative & Experimental Medicine at the College of Veterinary Medicine, The University of Tennessee. His doctoral research work focused on understanding the role of IL-17A and Th17 cells in herpes simplex virus 1-induced corneal immunopathology. As a postdoctoral research fellow at Tufts University School of Medicine, he is studying the role of host innate and adaptive immune response in mediating corneal pathology and vision impairment against various microbial infections of the cornea.

Biography
 Research Interest :

Host Pathogen Interaction and associated immunopathology. Infectious Blindness, Angiogenesis, Inflammation, Corneal Immunopathology, Infectious Diseases. Identifying novel molecular and cellular targets for pharmacological intervention of inflammatory conditions.

Research Interest
 Network
 
Md.Salahuddin

Md. Salahuddin
Department of Biological sciences
Sungkyunkwan University
Suwon, South Korea
Read Interview session with Md.Salahuddin

Sungkyunkwan University
 Biography :

DR. Md. Salahuddin is an immunophysiologist from Bangladesh. He is now an outstanding Foreign Research Scholars, Sungkyunkwan University, Korea. He obtained Doctor of Veterinary Medicine and MS in Physiology from Bangladesh Agricultural University. He has been working on immunophysiology of dendric cell and its role in cancer biology. His MS theses were involved in understanding effects of Protein, vitamin and probiotics in Animal health and diseases. He elucidated mechanism of the exact level of protein for the highest production of broiler weight. He has awarded a fellowship from National science and Technology Ministry of Bangladesh for his outstanding research (2011). Md participated in many international scientific seminars and symposium.

Biography
 Research Interest :

Immune-physiology, Dendritic cell, cancer and herbal medicine

Research Interest
 Network
 
Pankaj Sharma

Pankaj Sharma
Postdoctoral fellow
Center for cancer research and therapeutic development
Department of Biological Sciences
Clark Atlanta University
Atlanta, GA
 

Clark Atlanta University
 Biography :

Pankaj Sharma is currently working as a postdoctoral fellow since 2009, at center for cancer research and therapeutic development; Atlanta, GA. Interest in oncology research moved her from California to Georgia. Her first postdoctoral fellow position was in children’s hospital Oakland research institute, CA.There she worked on vaccine development of Chlamydia trachomatis. Although her first postdoctoral fellowship was for short period but she learned lot about protein research which influenced her towards the field of proteomics. Her recent research work is based on protein- protein interaction study of bHLH transcriptional regulators and study the effect of this interaction on Androgen signaling pathway in prostate cancer. She finished her doctoral degree (in Genetics with minor in biochemistry) from Chaudhary Charan Singh Haryana Agricultural University, India. Being from an agricultural state, her doctoral research work is based on the genetics and biochemistry of soil micro-organisms, which helps cultivated crops under drought stress conditions and can be used as a biofertilizers.She also received a university scholarship/award for this research program. She also served as a research associate in same university and then she moved to US, to explore the field of molecular biology. Personal interest includes cooking, traveling and music.

Biography
 Research Interest :

To understand molecular events where in a differentiated cell becomes undifferentiated, bypasses senescence, undergoes immortalization and eventually becomes transformed. By integrating a multitude of molecular, proteomic and genomic approaches to address the fundamental biology of these events that eventually leads to neoplastic transformation. The model systems that we use to address these molecular pathways are prostate cancer. Also how Id proteins helps in renewal and maintenance of stem cells. Interested in protein structural studies

Research Interest
 Network
 
Graziano Pinna

Graziano Pinna
Department of Psychiatry
University of Illinois
Chicago
Office Phone: 312-355-1464
E-mail:gpinna@psych.uic.edu 

University of Illinois
 Biography :
Biography
 Research Interest :

mouse models of post-traumatic stress disorder (PTSD); investigating the mechanism of action of antidepressants; developing new efficacious therapies for anxiety disorders and PTSD

Research Interest
 Network
 
Rammohan Devulapally

Rammohan Devulapally
Postdoctoral Research Fellow
Department of Radiology
Stanford University
California

 

Stanford University
 Biography :

Rammohan Devulapally received his Ph.D. in Synthetic Organic Chemistry from Department of Chemistry, National Chung Cheng University, Taiwan in 2009, under the guidance of Prof. Yung-Son Hon. His Ph.D. thesis work focused on TiCl4-promoted intramolecular cyclization reactions and their application in the total synthesis of natural products. After his PhD, he worked with Prof. Chung-Chen Liao as a postdoctoral fellow in Chung Yuan Christian University on masked ortho-benzoquinones (MOBs) and azulene chemistry in organic synthesis. Then, he moved to Texas A&M University at Qatar as a postdoctoral research associate, worked on synthesis and cross-coupling reactions of organotrifluoroborates with Prof. Dave Seapy and Prof. Gary Molander. Presently, he is working with Dr. Paulmurugan as a postdoctoral research fellow in Molecular Imaging Program at Stanford (MIPS) and Bio-X Program in Stanford University School of Medicine. His current research work focus on developing multifunctional polymer nanocarriers for the co-delivery of therapeutic microRNAs and drugs for hepatocellular carcinoma (HCC) and triple negative breast cancer treatment in pre-clinical small animal model. He is serving as an expert reviewers for journals like, The Journal of Organic Chemistry, Tetrahedron Letter, International Journal of Nanomedicine, and Biochemical Pharmacology. He has authored several research articles in journal like Tetrahedron Letter. WIREs Nanomedicine and Nanobiotechnology and Journal of Organic Chemistry. He is a member of American Chemical Society and World Molecular Imaging Society (WMIC).

Biography
 Research Interest :

His current research interests are applications of synthetic organic chemistry to bioorganic, medicinal chemistry, chemical biology, nanomedicine and biomedical research.

Research Interest
 Network
 
Yang Shun-Fa

Yang Shun-Fa
Director
Clinical Cancer Research
Chung Shan Medical University Hospital
Taiwan
E mail: ysf@csmu.edu.tw
 

Chung Shan Medical University
 Biography :

Yang is a professor of Institute of Medicine, Chung Shan Medical University, Taiwan. He has received the Ph.D. degree in molecular biology. In particular, his researches have been focused on pharmacology, cancer metastasis, cancer biology, genetic polymorphism and environment risk factors in cancer.

Biography
 Research Interest :

pharmacology, cancer metastasis, cancer biology, genetic polymorphism and environment risk factors in cancer

Research Interest
 Network
 
Malik Keshwani

Malik Keshwani
Post Doctoral Fellow
University of California, San Diego
California 92093-0636
Ph: 858-822-3706 (lab)
Fax: 858-534-8193
Tel: (786) 218-3799
Email: mkeshwani@ucsd.edu; malik.keshwani@gmail.com
 

University of California
 Biography :

• Expert in Mechanistic Enzymology and Signal transduction of Protein kinases in Cancer biology and Splicing
• Assay Development for kinases, phosphatases, Hydrolases, Ligases. Expert in Steady State, Pre-Steady State Enzyme Kinetics and Inhibition Assays
• Protein Protein interactions, RNA protein interactions, phosphatase, splicing, GTPase, ubiquitin degradation assay (radiometric and fluorescence based)
• Genetic Engineering and Protein Expression in prokaryotic and eukaryotic systems as well as in vitro transcription translation
• Mammalian cell culture and transient transfections, siRNA knockdown, RT-PCR
• Protein Purification using Affinity, Gel-Filtration, Ion-Exchange and Heparin chromatograpy; Protein characterization using ESI-TOF Mass Spectroscopy Western blot analysis, Phos-Tag SDS-PAGE
• Good knowledge of GPCR, G protein signaling, phosphatases, Ubiquitin ligase, transcription factors.
• Working knowledge of RASL-seq genome wide analysis, immunology and FACS, ITC, SPR, Nanochemistry (Quantum Dot synthesis), Fluorescence Resonance Energy Transfer, Peptide Synthesis, and Organic syntheses
 

Biography
 Research Interest :

To obtain an academic position that offers an opportunity in a challenging environment directed towards better understanding of molecular mechanisms of signaling cascades regulating mRNA alternative splicing and phospho-regulation of Splicing factors in Splicing.

Research Interest
 Network
 
Zainab Mahmood Aljamali

Zainab Mahmood Aljamali
Assistant Lecturer Prosthodontics
Dentistry department
University of Babylon, IRAQ.
Tel: 009647817340558
E-mail: Zainab.jouid@yahoo.com
 

University of Babylon
 Biography :

I am Dr. Zainab Mahmood Aljamali. I have Certificate in 2012, in prosthodontics, Dentistry. I have papers publication (4) articles in (prosthodontics and physiology).

Biography
 Research Interest :

prosthetic dentistry, dentistry treatment, biochemistry, Medicine field

Research Interest
 Network
 
 
 
 
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